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Fludarabine Inhibits K(V)1.3 Currents in Human B Lymphocytes
Fludarabine (F-ara-A) is a purine analog commonly used in the treatment of indolent B cell malignancies that interferes with different aspects of DNA and RNA synthesis. K(V)1.3 K(+) channels are membrane proteins involved in the maintenance of K(+) homeostasis and the resting potential of the cell,...
Autores principales: | de la Cruz, Alicia, Vera-Zambrano, Alba, Peraza, Diego A., Valenzuela, Carmen, Zapata, Juan M., Perez-Chacon, Gema, Gonzalez, Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374215/ https://www.ncbi.nlm.nih.gov/pubmed/28408885 http://dx.doi.org/10.3389/fphar.2017.00177 |
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