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Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat

We previously mapped hypertension-related insulin resistance quantitative trait loci (QTLs) to rat chromosomes 4, 12 and 16 using adipocytes from F2 crosses between spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats, and subsequently identified Cd36 as the gene underlying the chromosome 4...

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Detalles Bibliográficos
Autores principales: Coan, Philip M., Hummel, Oliver, Garcia Diaz, Ana, Barrier, Marjorie, Alfazema, Neza, Norsworthy, Penny J., Pravenec, Michal, Petretto, Enrico, Hübner, Norbert, Aitman, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374317/
https://www.ncbi.nlm.nih.gov/pubmed/28130354
http://dx.doi.org/10.1242/dmm.026716