Miconazole protects blood vessels from MMP9-dependent rupture and hemorrhage

Hemorrhagic stroke accounts for 10-15% of all strokes and is strongly associated with mortality and morbidity worldwide, but its prevention and therapeutic interventions remain a major challenge. Here, we report the identification of miconazole as a hemorrhagic suppressor by a small-molecule screen...

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Detalles Bibliográficos
Autores principales: Yang, Ran, Zhang, Yunpei, Huang, Dandan, Luo, Xiao, Zhang, Liangren, Zhu, Xiaojun, Zhang, Xiaolin, Liu, Zhenming, Han, Jing-Yan, Xiong, Jing-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374319/
https://www.ncbi.nlm.nih.gov/pubmed/28153846
http://dx.doi.org/10.1242/dmm.027268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374319/
https://www.ncbi.nlm.nih.gov/pubmed/28153846
http://dx.doi.org/10.1242/dmm.027268

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