Diabetic polyneuropathy, sensory neurons, nuclear structure and spliceosome alterations: a role for CWC22

Unique deficits in the function of adult sensory neurons as part of their early neurodegeneration might account for progressive polyneuropathy during chronic diabetes mellitus. Here, we provide structural and functional evidence for aberrant pre-mRNA splicing in a chronic type 1 model of experimenta...

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Detalles Bibliográficos
Autores principales: Kobayashi, Masaki, Chandrasekhar, Ambika, Cheng, Chu, Martinez, Jose A., Ng, Hilarie, de la Hoz, Cristiane, Zochodne, Douglas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374325/
https://www.ncbi.nlm.nih.gov/pubmed/28250049
http://dx.doi.org/10.1242/dmm.028225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374325/
https://www.ncbi.nlm.nih.gov/pubmed/28250049
http://dx.doi.org/10.1242/dmm.028225

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