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Diabetic polyneuropathy, sensory neurons, nuclear structure and spliceosome alterations: a role for CWC22
Unique deficits in the function of adult sensory neurons as part of their early neurodegeneration might account for progressive polyneuropathy during chronic diabetes mellitus. Here, we provide structural and functional evidence for aberrant pre-mRNA splicing in a chronic type 1 model of experimenta...
Autores principales: | Kobayashi, Masaki, Chandrasekhar, Ambika, Cheng, Chu, Martinez, Jose A., Ng, Hilarie, de la Hoz, Cristiane, Zochodne, Douglas W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374325/ https://www.ncbi.nlm.nih.gov/pubmed/28250049 http://dx.doi.org/10.1242/dmm.028225 |
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