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Severe pre-eclampsia is associated with alterations in cytotrophoblasts of the smooth chorion

Pre-eclampsia (PE), which affects ∼8% of first pregnancies, is associated with faulty placentation. Extravillous cytotrophoblasts (CTBs) fail to differentiate properly, contributing to shallow uterine invasion and deficient spiral artery remodeling. We studied the effects of severe PE (sPE) on the s...

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Detalles Bibliográficos
Autores principales: Garrido-Gomez, Tamara, Ona, Katherine, Kapidzic, Mirhan, Gormley, Matthew, Simón, Carlos, Genbacev, Olga, Fisher, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374356/
https://www.ncbi.nlm.nih.gov/pubmed/28232601
http://dx.doi.org/10.1242/dev.146100