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Investigation of Drug–Polymer Compatibility Using Chemometric-Assisted UV-Spectrophotometry

A simple chemometric-assisted UV-spectrophotometric method was used to study the compatibility of clindamycin hydrochloride (HC1) with two commonly used natural controlled-release polymers, alginate (Ag) and chitosan (Ch). Standard mixtures containing 1:1, 1:2, and 1:0.5 w/w drug–polymer ratios were...

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Detalles Bibliográficos
Autores principales: Mohamed, Amir Ibrahim, Abd-Motagaly, Amr Mohamed Elsayed, Ahmed, Osama A. A., Amin, Suzan, Mohamed Ali, Alaa Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374373/
https://www.ncbi.nlm.nih.gov/pubmed/28275214
http://dx.doi.org/10.3390/pharmaceutics9010007