Biomarker-Guided Non-Adaptive Trial Designs in Phase II and Phase III: A Methodological Review

Biomarker-guided treatment is a rapidly developing area of medicine, where treatment choice is personalised according to one or more of an individual’s biomarker measurements. A number of biomarker-guided trial designs have been proposed in the past decade, including both adaptive and non-adaptive t...

Descripción completa

Detalles Bibliográficos
Autores principales: Antoniou, Miranta, Kolamunnage-Dona, Ruwanthi, Jorgensen, Andrea L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374391/
https://www.ncbi.nlm.nih.gov/pubmed/28125057
http://dx.doi.org/10.3390/jpm7010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374391/
https://www.ncbi.nlm.nih.gov/pubmed/28125057
http://dx.doi.org/10.3390/jpm7010001

Ejemplares similares