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Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly

Cardiac development in vertebrates is a finely tuned process regulated by a set of conserved signaling pathways. Perturbations of these processes are often associated with congenital cardiac malformations. Platelet-derived growth factor receptor α (PDGFRα) is a highly conserved tyrosine kinase recep...

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Detalles Bibliográficos
Autores principales: El-Rass, Suzan, Eisa-Beygi, Shahram, Khong, Edbert, Brand-Arzamendi, Koroboshka, Mauro, Antonio, Zhang, Haibo, Clark, Karl J., Ekker, Stephen C., Wen, Xiao-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374395/
https://www.ncbi.nlm.nih.gov/pubmed/28167492
http://dx.doi.org/10.1242/bio.021212