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The Phosphorylation of PDX-1 by Protein Kinase CK2 Is Crucial for Its Stability

The homeodomain protein PDX-1 is a critical regulator of pancreatic development and insulin production in pancreatic β-cells. We have recently shown that PDX-1 is a substrate of protein kinase CK2; a multifunctional protein kinase which is implicated in the regulation of various cellular aspects, su...

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Detalles Bibliográficos
Autores principales: Klein, Sabrina, Meng, Rui, Montenarh, Mathias, Götz, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374406/
https://www.ncbi.nlm.nih.gov/pubmed/28036027
http://dx.doi.org/10.3390/ph10010002