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The Phosphorylation of PDX-1 by Protein Kinase CK2 Is Crucial for Its Stability
The homeodomain protein PDX-1 is a critical regulator of pancreatic development and insulin production in pancreatic β-cells. We have recently shown that PDX-1 is a substrate of protein kinase CK2; a multifunctional protein kinase which is implicated in the regulation of various cellular aspects, su...
Autores principales: | Klein, Sabrina, Meng, Rui, Montenarh, Mathias, Götz, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374406/ https://www.ncbi.nlm.nih.gov/pubmed/28036027 http://dx.doi.org/10.3390/ph10010002 |
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