Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining

Protein kinase CK2, initially designated as casein kinase 2, is an ubiquitously expressed serine/threonine kinase. This enzyme, implicated in many cellular processes, is highly expressed and active in many tumor cells. A large number of compounds has been developed as inhibitors comprising different...

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Detalles Bibliográficos
Autores principales: Haidar, Samer, Bouaziz, Zouhair, Marminon, Christelle, Laitinen, Tuomo, Poso, Antti, Le Borgne, Marc, Jose, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374412/
https://www.ncbi.nlm.nih.gov/pubmed/28075359
http://dx.doi.org/10.3390/ph10010008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374412/
https://www.ncbi.nlm.nih.gov/pubmed/28075359
http://dx.doi.org/10.3390/ph10010008

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