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Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers
The malaria liver stage is an attractive target for antimalarial development, and preclinical malaria models are essential for testing such candidates. Given ethical concerns and costs associated with non‐human primate models, humanized mouse models containing chimeric human livers offer a valuable...
Autores principales: | Ng, Shengyong, March, Sandra, Galstian, Ani, Gural, Nil, Stevens, Kelly R., Mota, Maria M., Bhatia, Sangeeta N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374446/ https://www.ncbi.nlm.nih.gov/pubmed/28361899 http://dx.doi.org/10.1038/srep45424 |
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