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Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection
Widespread gene transfer to the retina is challenging as it requires vector systems to overcome physical and biochemical barriers to enter and diffuse throughout retinal tissue. We investigated whether exosome-associated adeno-associated virus, (exo-AAV) enabled broad retinal targeting following int...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374486/ https://www.ncbi.nlm.nih.gov/pubmed/28361998 http://dx.doi.org/10.1038/srep45329 |