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Sedentary lifestyle related exosomal release of Hotair from gluteal-femoral fat promotes intestinal cell proliferation

Pioneering epidemiological work has established strong association of sedentary lifestyle and obesity with the risk of colorectal cancer, while the detailed underlying mechanism remains unknown. Here we show that Hotair (HOX transcript antisense RNA) is a pro-adipogenic long non-coding RNA highly ex...

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Detalles Bibliográficos
Autores principales: Lu, Xiaozhao, Bai, Danna, Liu, Xiangwei, Zhou, Chen, Yang, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374500/
https://www.ncbi.nlm.nih.gov/pubmed/28361920
http://dx.doi.org/10.1038/srep45648