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Cell-to-cell transfer of SAA1 protein in a cell culture model of systemic AA amyloidosis

Systemic AA amyloidosis arises from the misfolding of serum amyloid A1 (SAA1) protein and the deposition of AA amyloid fibrils at multiple sites within the body. Previous research already established that mononuclear phagocytes are crucial for the formation of the deposits in vivo and exposure of cu...

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Detalles Bibliográficos
Autores principales: Claus, Stephanie, Puscalau-Girtu, Ioana, Walther, Paul, Syrovets, Tatiana, Simmet, Thomas, Haupt, Christian, Fändrich, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374501/
https://www.ncbi.nlm.nih.gov/pubmed/28361953
http://dx.doi.org/10.1038/srep45683