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Genomic structure of the horse major histocompatibility complex class II region resolved using PacBio long-read sequencing technology

The mammalian Major Histocompatibility Complex (MHC) region contains several gene families characterized by highly polymorphic loci with extensive nucleotide diversity, copy number variation of paralogous genes, and long repetitive sequences. This structural complexity has made it difficult to const...

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Detalles Bibliográficos
Autores principales: Viļuma, Agnese, Mikko, Sofia, Hahn, Daniela, Skow, Loren, Andersson, Göran, Bergström, Tomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374520/
https://www.ncbi.nlm.nih.gov/pubmed/28361880
http://dx.doi.org/10.1038/srep45518