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Genomic structure of the horse major histocompatibility complex class II region resolved using PacBio long-read sequencing technology
The mammalian Major Histocompatibility Complex (MHC) region contains several gene families characterized by highly polymorphic loci with extensive nucleotide diversity, copy number variation of paralogous genes, and long repetitive sequences. This structural complexity has made it difficult to const...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374520/ https://www.ncbi.nlm.nih.gov/pubmed/28361880 http://dx.doi.org/10.1038/srep45518 |