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IgE binds asymmetrically to its B cell receptor CD23

The antibody IgE plays a central role in allergic disease mechanisms. Its effector functions are controlled through interactions between the Fc region and two principal cell surface receptors FcεRI and CD23. The interaction with FcεRI is primarily responsible for allergic sensitization and the infla...

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Detalles Bibliográficos
Autores principales: Dhaliwal, Balvinder, Pang, Marie O. Y., Keeble, Anthony H., James, Louisa K., Gould, Hannah J., McDonnell, James M., Sutton, Brian J., Beavil, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374546/
https://www.ncbi.nlm.nih.gov/pubmed/28361904
http://dx.doi.org/10.1038/srep45533