Cargando…
IgE binds asymmetrically to its B cell receptor CD23
The antibody IgE plays a central role in allergic disease mechanisms. Its effector functions are controlled through interactions between the Fc region and two principal cell surface receptors FcεRI and CD23. The interaction with FcεRI is primarily responsible for allergic sensitization and the infla...
Autores principales: | Dhaliwal, Balvinder, Pang, Marie O. Y., Keeble, Anthony H., James, Louisa K., Gould, Hannah J., McDonnell, James M., Sutton, Brian J., Beavil, Andrew J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374546/ https://www.ncbi.nlm.nih.gov/pubmed/28361904 http://dx.doi.org/10.1038/srep45533 |
Ejemplares similares
-
Conformational plasticity at the IgE-binding site of the B-cell receptor CD23()
por: Dhaliwal, Balvinder, et al.
Publicado: (2013) -
Mapping of the CD23 Binding Site on Immunoglobulin E (IgE) and Allosteric Control of the IgE-FcϵRI Interaction
por: Borthakur, Susmita, et al.
Publicado: (2012) -
A range of C∊3–C∊4 interdomain angles in IgE Fc accommodate binding to its receptor CD23
por: Dhaliwal, Balvinder, et al.
Publicado: (2014) -
The structure of human CD23 and its interactions with IgE and CD21
por: Hibbert, Richard G., et al.
Publicado: (2005) -
Reviving lost binding sites: Exploring calcium‐binding site transitions between human and murine CD23
por: Ilkow, Veronica F., et al.
Publicado: (2021)