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Identifying miRNA sponge modules using biclustering and regulatory scores

BACKGROUND: MicroRNA (miRNA) sponges with multiple tandem miRNA binding sequences can sequester miRNAs from their endogenous target mRNAs. Therefore, miRNA sponge acting as a decoy is extremely important for long-term loss-of-function studies both in vivo and in silico. Recently, a growing number of...

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Detalles Bibliográficos
Autores principales: Zhang, Junpeng, Le, Thuc D, Liu, Lin, Li, Jiuyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374547/
https://www.ncbi.nlm.nih.gov/pubmed/28361682
http://dx.doi.org/10.1186/s12859-017-1467-5