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The synthetic peptide CIGB-300 modulates CK2-dependent signaling pathways affecting the survival and chemoresistance of non-small cell lung cancer cell lines

BACKGROUND: Lung cancer is the most frequently diagnosed cancer and the leading cause of cancer-related deaths worldwide. Up to 80% of cancer patients are classified as non-small-cell lung cancer (NSCLC) and cisplatin remains as the gold standard chemotherapy treatment, despite its limited efficacy...

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Detalles Bibliográficos
Autores principales: Cirigliano, Stéfano M., Díaz Bessone, María I., Berardi, Damián E., Flumian, Carolina, Bal de Kier Joffé, Elisa D., Perea, Silvio E., Farina, Hernán G., Todaro, Laura B., Urtreger, Alejandro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374619/
https://www.ncbi.nlm.nih.gov/pubmed/28373828
http://dx.doi.org/10.1186/s12935-017-0413-y