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An integrated approach with new strategies for QSAR models and lead optimization
BACKGROUND: Computational drug design approaches are important for shortening the time and reducing the cost for drug discovery and development. Among these methods, molecular docking and quantitative structure activity relationship (QSAR) play key roles for lead discovery and optimization. Here, we...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374651/ https://www.ncbi.nlm.nih.gov/pubmed/28361681 http://dx.doi.org/10.1186/s12864-017-3503-2 |