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An integrated approach with new strategies for QSAR models and lead optimization

BACKGROUND: Computational drug design approaches are important for shortening the time and reducing the cost for drug discovery and development. Among these methods, molecular docking and quantitative structure activity relationship (QSAR) play key roles for lead discovery and optimization. Here, we...

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Detalles Bibliográficos
Autores principales:	Hsu, Hui-Hui, Hsu, Yen-Chao, Chang, Li-Jen, Yang, Jinn-Moon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374651/ https://www.ncbi.nlm.nih.gov/pubmed/28361681 http://dx.doi.org/10.1186/s12864-017-3503-2

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