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A statistical method for the conservative adjustment of false discovery rate (q-value)

BACKGROUND: q-value is a widely used statistical method for estimating false discovery rate (FDR), which is a conventional significance measure in the analysis of genome-wide expression data. q-value is a random variable and it may underestimate FDR in practice. An underestimated FDR can lead to une...

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Detalles Bibliográficos
Autor principal:	Lai, Yinglei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374657/ https://www.ncbi.nlm.nih.gov/pubmed/28361675 http://dx.doi.org/10.1186/s12859-017-1474-6

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