Protein complex-based analysis is resistant to the obfuscating consequences of batch effects --- a case study in clinical proteomics

BACKGROUND: In proteomics, batch effects are technical sources of variation that confounds proper analysis, preventing effective deployment in clinical and translational research. RESULTS: Using simulated and real data, we demonstrate existing batch effect-correction methods do not always eradicate...

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Detalles Bibliográficos
Autores principales: Goh, Wilson Wen Bin, Wong, Limsoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374662/
https://www.ncbi.nlm.nih.gov/pubmed/28361693
http://dx.doi.org/10.1186/s12864-017-3490-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374662/
https://www.ncbi.nlm.nih.gov/pubmed/28361693
http://dx.doi.org/10.1186/s12864-017-3490-3

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