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Protein complex-based analysis is resistant to the obfuscating consequences of batch effects --- a case study in clinical proteomics
BACKGROUND: In proteomics, batch effects are technical sources of variation that confounds proper analysis, preventing effective deployment in clinical and translational research. RESULTS: Using simulated and real data, we demonstrate existing batch effect-correction methods do not always eradicate...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374662/ https://www.ncbi.nlm.nih.gov/pubmed/28361693 http://dx.doi.org/10.1186/s12864-017-3490-3 |