Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer

BACKGROUND: Epigenetic information can be used to identify clinically relevant genomic variants single nucleotide polymorphisms (SNPs) of functional importance in cancer development. Super-enhancers are cell-specific DNA elements, acting to determine tissue or cell identity and driving tumor progres...

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Detalles Bibliográficos
Autores principales: Zuber, Verena, Bettella, Francesco, Witoelar, Aree, Andreassen, Ole A., Mills, Ian G., Urbanucci, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374680/
https://www.ncbi.nlm.nih.gov/pubmed/28359301
http://dx.doi.org/10.1186/s12864-017-3620-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374680/
https://www.ncbi.nlm.nih.gov/pubmed/28359301
http://dx.doi.org/10.1186/s12864-017-3620-y

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