A computational method for estimating the PCR duplication rate in DNA and RNA-seq experiments

BACKGROUND: PCR amplification is an important step in the preparation of DNA sequencing libraries prior to high-throughput sequencing. PCR amplification introduces redundant reads in the sequence data and estimating the PCR duplication rate is important to assess the frequency of such reads. Existin...

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Detalles Bibliográficos
Autor principal: Bansal, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374682/
https://www.ncbi.nlm.nih.gov/pubmed/28361665
http://dx.doi.org/10.1186/s12859-017-1471-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374682/
https://www.ncbi.nlm.nih.gov/pubmed/28361665
http://dx.doi.org/10.1186/s12859-017-1471-9

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