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Staged heterogeneity learning to identify conformational B-cell epitopes from antigen sequences

BACKGROUND: The broad heterogeneity of antigen-antibody interactions brings tremendous challenges to the design of a widely applicable learning algorithm to identify conformational B-cell epitopes. Besides the intrinsic heterogeneity introduced by diverse species, extra heterogeneity can also be int...

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Detalles Bibliográficos
Autores principales: Ren, Jing, Song, Jiangning, Ellis, John, Li, Jinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374683/
https://www.ncbi.nlm.nih.gov/pubmed/28361709
http://dx.doi.org/10.1186/s12864-017-3493-0