Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat

BACKGROUND: MyD88 is the adaptor protein of MyD88-dependent signaling pathway of TLRs and IL-1 receptor and regulates innate immune response. However, it was not clear whether and how MyD88 and related signaling pathways in the dorsal root ganglion (DRG) and spinal dorsal horn (SDH) are involved in...

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Detalles Bibliográficos
Autores principales: Liu, Fan, Wang, Zhiyao, Qiu, Yue, Wei, Min, Li, Chunyan, Xie, Yikuan, Shen, Le, Huang, Yuguang, Ma, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374701/
https://www.ncbi.nlm.nih.gov/pubmed/28359290
http://dx.doi.org/10.1186/s12974-017-0822-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374701/
https://www.ncbi.nlm.nih.gov/pubmed/28359290
http://dx.doi.org/10.1186/s12974-017-0822-9

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