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Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat
BACKGROUND: MyD88 is the adaptor protein of MyD88-dependent signaling pathway of TLRs and IL-1 receptor and regulates innate immune response. However, it was not clear whether and how MyD88 and related signaling pathways in the dorsal root ganglion (DRG) and spinal dorsal horn (SDH) are involved in...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374701/ https://www.ncbi.nlm.nih.gov/pubmed/28359290 http://dx.doi.org/10.1186/s12974-017-0822-9 |