Combination therapy design for maximizing sensitivity and minimizing toxicity

BACKGROUND: Design of personalized targeted therapies involve modeling of patient sensitivity to various drugs and drug combinations. Majority of studies evaluate the sensitivity of tumor cells to targeted drugs without modeling the effect of the drugs on normal cells. In this article, we consider t...

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Detalles Bibliográficos
Autores principales: Matlock, Kevin, Berlow, Noah, Keller, Charles, Pal, Ranadip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374708/
https://www.ncbi.nlm.nih.gov/pubmed/28361667
http://dx.doi.org/10.1186/s12859-017-1523-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374708/
https://www.ncbi.nlm.nih.gov/pubmed/28361667
http://dx.doi.org/10.1186/s12859-017-1523-1

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