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Combination therapy design for maximizing sensitivity and minimizing toxicity
BACKGROUND: Design of personalized targeted therapies involve modeling of patient sensitivity to various drugs and drug combinations. Majority of studies evaluate the sensitivity of tumor cells to targeted drugs without modeling the effect of the drugs on normal cells. In this article, we consider t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374708/ https://www.ncbi.nlm.nih.gov/pubmed/28361667 http://dx.doi.org/10.1186/s12859-017-1523-1 |