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Role of Conformational Motions in Enzyme Function: Selected Methodologies and Case Studies

It is now common knowledge that enzymes are mobile entities relying on complex atomic-scale dynamics and coordinated conformational events for proper ligand recognition and catalysis. However, the exact role of protein dynamics in enzyme function remains either poorly understood or difficult to inte...

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Detalles Bibliográficos
Autores principales: Narayanan, Chitra, Bernard, David N., Doucet, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375114/
https://www.ncbi.nlm.nih.gov/pubmed/28367322
http://dx.doi.org/10.3390/catal6060081