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Prediction of diuretic response to tolvaptan by a simple, readily available spot urine Na/K ratio

BACKGROUND: Tolvaptan is vasopressin type 2 receptor antagonist that inhibits water reabsorption. It is used in combination with standard diuretics to treat ascites unresponsive to standard diuretic therapy or hyponatremia because of liver cirrhosis. This study evaluated the effectiveness and safety...

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Detalles Bibliográficos
Autores principales: Komiyama, Yasuyuki, Kurosaki, Masayuki, Nakanishi, Hiroyuki, Takahashi, Yuka, Itakura, Jun, Yasui, Yutaka, Tamaki, Nobuharu, Takada, Hitomi, Higuchi, Mayu, Gotou, Tomoyuki, Kubota, Youhei, Takaura, Kenta, Hayashi, Tsuguru, Oh, Wann, Okada, Mao, Enomoto, Nobuyuki, Izumi, Namiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375149/
https://www.ncbi.nlm.nih.gov/pubmed/28362879
http://dx.doi.org/10.1371/journal.pone.0174649