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Extensive telomere erosion is consistent with localised clonal expansions in Barrett’s metaplasia

Barrett’s oesophagus is a premalignant metaplastic condition that predisposes patients to the development of oesophageal adenocarcinoma. However, only a minor fraction of Barrett’s oesophagus patients progress to adenocarcinoma and it is thus essential to determine bio-molecular markers that can pre...

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Detalles Bibliográficos
Autores principales: Letsolo, Boitelo T., Jones, Rhiannon E., Rowson, Jan, Grimstead, Julia W., Keith, W. Nicol, Jenkins, Gareth J. S., Baird, Duncan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375150/
https://www.ncbi.nlm.nih.gov/pubmed/28362812
http://dx.doi.org/10.1371/journal.pone.0174833