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Toll-Like Receptor 7 Agonist GS-9620 Induces HIV Expression and HIV-Specific Immunity in Cells from HIV-Infected Individuals on Suppressive Antiretroviral Therapy

Antiretroviral therapy can suppress HIV replication to undetectable levels but does not eliminate latent HIV, thus necessitating lifelong therapy. Recent efforts to target this persistent reservoir have focused on inducing the expression of latent HIV so that infected cells may be recognized and eli...

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Detalles Bibliográficos
Autores principales: Tsai, Angela, Irrinki, Alivelu, Kaur, Jasmine, Cihlar, Tomas, Kukolj, George, Sloan, Derek D., Murry, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375698/
https://www.ncbi.nlm.nih.gov/pubmed/28179531
http://dx.doi.org/10.1128/JVI.02166-16