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Developing Hypothetical Inhibition Mechanism of Novel Urea Transporter B Inhibitor

Urea transporter B (UT-B) is a membrane channel protein that specifically transports urea. UT-B null mouse exhibited urea selective urine concentrating ability deficiency, which suggests the potential clinical applications of the UT-B inhibitors as novel diuretics. Primary high-throughput virtual sc...

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Detalles Bibliográficos
Autores principales: Li, Min, Tou, Weng Ieong, Zhou, Hong, Li, Fei, Ren, Huiwen, Chen, Calvin Yu-Chian, Yang, Baoxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376056/
https://www.ncbi.nlm.nih.gov/pubmed/25047372
http://dx.doi.org/10.1038/srep05775