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Protective Effect of Aframomum melegueta phenolics Against CCl(4)-Induced Rat Hepatocytes Damage; Role of Apoptosis and Pro-inflammatory Cytokines inhibition

Aframomum melegueta is a commonly used African spice. Through a hepatoprotective bioassay-guided isolation, the chloroform fraction of A.melegueta seeds yielded one new diarylheptanoid named 3-(S)-acetyl-1-(4′-hydroxy-3′, 5′-di methoxyphenyl)-7-(3″,4″, 5″-trihydroxyphenyl)heptane (1), and two new hy...

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Detalles Bibliográficos
Autores principales: El-Halawany, Ali M., Dine, Riham Salah El, El Sayed, Nesrine S., Hattori, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376205/
https://www.ncbi.nlm.nih.gov/pubmed/25077538
http://dx.doi.org/10.1038/srep05880