Hyaluronic acid–nimesulide conjugates as anticancer drugs against CD44-overexpressing HT-29 colorectal cancer in vitro and in vivo

Carrier-mediated drug delivery systems are promising therapeutics for targeted delivery and improved efficacy and safety of potent cytotoxic drugs. Nimesulide is a multifactorial cyclooxygenase 2 nonsteroidal anti-inflammatory drug with analgesic, antipyretic and potent anticancer properties; howeve...

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Detalles Bibliográficos
Autores principales: Jian, You-Sin, Chen, Ching-Wen, Lin, Chih-An, Yu, Hsiu-Ping, Lin, Hua-Yang, Liao, Ming-Yuan, Wu, Shu-Huan, Lin, Yan-Fu, Lai, Ping-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376212/
https://www.ncbi.nlm.nih.gov/pubmed/28392690
http://dx.doi.org/10.2147/IJN.S120847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376212/
https://www.ncbi.nlm.nih.gov/pubmed/28392690
http://dx.doi.org/10.2147/IJN.S120847

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