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Atomic resolution structures from fragmented protein crystals by the cryoEM method MicroED
Crystallographic analysis of macromolecules depends on large, well-ordered crystals, which often require significant effort to obtain. Even sizable crystals sometimes suffer from pathologies that render them inappropriate for high-resolution structure determination. Here we show that fragmentation o...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376236/ https://www.ncbi.nlm.nih.gov/pubmed/28192420 http://dx.doi.org/10.1038/nmeth.4178 |