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Deep sequencing is an appropriate tool for the selection of unique Hepatitis C virus (HCV) variants after single genomic amplification

Hepatitis C virus (HCV) evolves rapidly in a single host and circulates as a quasispecies wich is a complex mixture of genetically distinct virus’s but closely related namely variants. To identify intra-individual diversity and investigate their functional properties in vitro, it is necessary to def...

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Detalles Bibliográficos
Autores principales: Guinoiseau, Thibault, Moreau, Alain, Hohnadel, Guillaume, Ngo-Giang-Huong, Nicole, Brulard, Celine, Vourc’h, Patrick, Goudeau, Alain, Gaudy-Graffin, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376297/
https://www.ncbi.nlm.nih.gov/pubmed/28362878
http://dx.doi.org/10.1371/journal.pone.0174852