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Novel phosphate-activated macrophages prevent ectopic calcification by increasing extracellular ATP and pyrophosphate
PURPOSE: Phosphorus is an essential nutrient involved in many pathobiological processes. Less than 1% of phosphorus is found in extracellular fluids as inorganic phosphate ion (Pi) in solution. High serum Pi level promotes ectopic calcification in many tissues, including blood vessels. Here, we stud...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376322/ https://www.ncbi.nlm.nih.gov/pubmed/28362852 http://dx.doi.org/10.1371/journal.pone.0174998 |