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Novel phosphate-activated macrophages prevent ectopic calcification by increasing extracellular ATP and pyrophosphate
PURPOSE: Phosphorus is an essential nutrient involved in many pathobiological processes. Less than 1% of phosphorus is found in extracellular fluids as inorganic phosphate ion (Pi) in solution. High serum Pi level promotes ectopic calcification in many tissues, including blood vessels. Here, we stud...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376322/ https://www.ncbi.nlm.nih.gov/pubmed/28362852 http://dx.doi.org/10.1371/journal.pone.0174998 |