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Ubiquitously expressed Human Beta Defensin 1 (hBD1) forms bacteria-entrapping nets in a redox dependent mode of action

Ever since the discovery of endogenous host defense antimicrobial peptides it has been discussed how these evolutionary conserved molecules avoid to induce resistance and to remain effective. Human ß-defensin 1 (hBD1) is an ubiquitously expressed endogenous antimicrobial peptide that exhibits qualit...

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Detalles Bibliográficos
Autores principales: Raschig, Judith, Mailänder-Sánchez, Daniela, Berscheid, Anne, Berger, Jürgen, Strömstedt, Adam A., Courth, Lioba F., Malek, Nisar P., Brötz-Oesterhelt, Heike, Wehkamp, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376342/
https://www.ncbi.nlm.nih.gov/pubmed/28323883
http://dx.doi.org/10.1371/journal.ppat.1006261