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Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells
The ability to build in-depth cell signaling networks from vast experimental data is a key objective of computational biology. The spleen tyrosine kinase (Syk) protein, a well-characterized key player in immune cell signaling, was surprisingly first shown by our group to exhibit an onco-suppressive...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376343/ https://www.ncbi.nlm.nih.gov/pubmed/28306714 http://dx.doi.org/10.1371/journal.pcbi.1005432 |