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Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells

The ability to build in-depth cell signaling networks from vast experimental data is a key objective of computational biology. The spleen tyrosine kinase (Syk) protein, a well-characterized key player in immune cell signaling, was surprisingly first shown by our group to exhibit an onco-suppressive...

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Detalles Bibliográficos
Autores principales: Naldi, Aurélien, Larive, Romain M., Czerwinska, Urszula, Urbach, Serge, Montcourrier, Philippe, Roy, Christian, Solassol, Jérôme, Freiss, Gilles, Coopman, Peter J., Radulescu, Ovidiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376343/
https://www.ncbi.nlm.nih.gov/pubmed/28306714
http://dx.doi.org/10.1371/journal.pcbi.1005432