Genetic ablation of the mammalian sterile-20 like kinase 1 (Mst1) improves cell reprogramming efficiency and increases induced pluripotent stem cell proliferation and survival

Adult fibroblasts can be reprogrammed into induced pluripotent stem cells (iPSC) for use in various applications. However, there are challenges in iPSC generation including low reprogramming efficiency, yield, cell survival and viability. Since the Hippo signalling pathway is a key pathway involved...

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Detalles Bibliográficos
Autores principales: Robertson, Abigail, Mohamed, Tamer M.A., El Maadawi, Zeinab, Stafford, Nicholas, Bui, Thuy, Lim, Dae-Sik, Cartwright, Elizabeth J., Oceandy, Delvac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Methods and Reagents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376382/
https://www.ncbi.nlm.nih.gov/pubmed/28257933
http://dx.doi.org/10.1016/j.scr.2017.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376382/
https://www.ncbi.nlm.nih.gov/pubmed/28257933
http://dx.doi.org/10.1016/j.scr.2017.02.011

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