The multistate tuberculosis pharmacometric model: a semi-mechanistic pharmacokinetic-pharmacodynamic model for studying drug effects in an acute tuberculosis mouse model

The Multistate Tuberculosis Pharmacometric (MTP) model, a pharmacokinetic-pharmacodynamic disease model, has been used to describe the effects of rifampicin on Mycobacterium tuberculosis (M. tuberculosis) in vitro. The aim of this work was to investigate if the MTP model could be used to describe th...

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Detalles Bibliográficos
Autores principales: Chen, Chunli, Ortega, Fatima, Rullas, Joaquin, Alameda, Laura, Angulo-Barturen, Iñigo, Ferrer, Santiago, Simonsson, Ulrika SH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376397/
https://www.ncbi.nlm.nih.gov/pubmed/28205025
http://dx.doi.org/10.1007/s10928-017-9508-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376397/
https://www.ncbi.nlm.nih.gov/pubmed/28205025
http://dx.doi.org/10.1007/s10928-017-9508-2

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