Activation of Adhesion GPCR EMR2/ADGRE2 Induces Macrophage Differentiation and Inflammatory Responses via Gα(16)/Akt/MAPK/NF-κB Signaling Pathways

EMR2/ADGRE2 is a human myeloid-restricted adhesion G protein-coupled receptor critically implicated in vibratory urticaria, a rare type of allergy caused by vibration-induced mast cell activation. In addition, EMR2 is also highly expressed by monocyte/macrophages and has been linked to neutrophil mi...

Descripción completa

Detalles Bibliográficos
Autores principales: I, Kuan-Yu, Huang, Yi-Shu, Hu, Ching-Hsun, Tseng, Wen-Yi, Cheng, Chia-Hsin, Stacey, Martin, Gordon, Siamon, Chang, Gin-Wen, Lin, Hsi-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376562/
https://www.ncbi.nlm.nih.gov/pubmed/28421075
http://dx.doi.org/10.3389/fimmu.2017.00373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376562/
https://www.ncbi.nlm.nih.gov/pubmed/28421075
http://dx.doi.org/10.3389/fimmu.2017.00373

Ejemplares similares