Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don’t Forget the Fuel

T-cells play a critical role in tumor immunity. Indeed, the presence of tumor-infiltrating lymphocytes is a predictor of favorable patient prognosis for many indications and is a requirement for responsiveness to immune checkpoint blockade therapy targeting programmed cell death 1. For tumors lackin...

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Detalles Bibliográficos
Autores principales: Irving, Melita, Vuillefroy de Silly, Romain, Scholten, Kirsten, Dilek, Nahzli, Coukos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376574/
https://www.ncbi.nlm.nih.gov/pubmed/28421069
http://dx.doi.org/10.3389/fimmu.2017.00267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376574/
https://www.ncbi.nlm.nih.gov/pubmed/28421069
http://dx.doi.org/10.3389/fimmu.2017.00267

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